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Charting the Landscape of Real-World Data in the United States

Explore how real-world data (RWD) is transforming healthcare and life sciences in Charting the Landscape of Real-World Data in the U.S. by Polygon Health Analytics. This white paper maps key data sources, highlights practical applications across sectors, and addresses challenges in access, quality, and analytics. Whether you’re a researcher, clinician, policymaker, or data strategist, this guide offers actionable insights and best practices for leveraging RWD to drive innovation, equity, and evidence-based decisions. Download now to stay ahead in the evolving data-driven healthcare ecosystem.

The Devil Lives in the Details: Why Data Quality Matters in Clinical Research

Feb 11, 2026

ClinicalTrials.gov is one of the most widely used clinical trial registries in the world. Biopharmaceutical companies, academic researchers, contract research organizations, patients—and increasingly AI...

PHA LaunchPad Program — Now Recruiting for the 2026 Summer Cohort

Jan 25, 2026

Location: Remote Duration: 3–6 months (part-time or full-time) Start Date: TBA (based on student team availability in the summer) Now entering its third year, the...

Celebrating 3 Years of Polygon Health Analytics

Jan 13, 2026

From corporate scientist to health tech founder: a candid three-year journey of building Polygon Health Analytics, transforming data, and redefining leadership....

Synthetic Data vs. Real-World Data: A Reality Check for Healthcare AI

Dec 15, 2025

I first encountered the concept of synthetic data back in 2013, while teaching a health informatics course as a tenure-track assistant professor at UNC Charlotte. To...

Drug Development Program Done Right: A Practical Checklist to Prevent Strategic Blind Spots

Nov 28, 2025

In the high-stakes world of pharmaceutical R&D, thousands of drug candidates are abandoned every year long before reaching patients. The harsh reality: fewer than...

QALYs Explained: The Metric That’s Shaping—and Dividing—Healthcare Policy

Nov 10, 2025

Quality-Adjusted Life Years (QALYs) are a cornerstone concept in health economics. They measure the value of medical treatments by considering both how long people live and...

Value-Based Health Care: Shifting the Focus from Quantity to Quality

Oct 23, 2025

Understand how value-based health care shifts focus from volume to outcomes, rewarding better results, reducing costs and improving patient care....

Budget Impact Models: A Practical Tool for Healthcare Decision-Making

Oct 07, 2025

Learn how Budget Impact Models help payers and HTA agencies assess short-term affordability of new healthcare treatments alongside cost-effectiveness analysis....

New White Paper: Charting the Landscape of Real-World Data in the U.S.

Oct 01, 2025

Learn how real-world data is transforming U.S. healthcare and life sciences. Our new white paper maps datasets, applications, challenges, and future directions....

Chart showing global vaccine trial trends

Polygon Health Analytics Launches Vaccine Trial Atlas: Making Clinical Trial Data Accessible

Sep 16, 2025

The vaccine research and development community has faced unprecedented challenges in recent months, including policy upheavals, leadership changes, research program cancellations, and a surge of misinformation...

Polygon Health Analytics Celebrates Graduation of 2025 Launchpad Cohort

Sep 03, 2025

[Philadelphia, September 2, 2025] – Polygon Health Analytics proudly announces the successful graduation of its 2025 Launchpad Program cohort—the second since the program’s inception—marking...

Patient-Reported Outcomes: Bringing the Patient’s Voice into Clinical Development and Outcomes Research

Aug 14, 2025

When it comes to healthcare, numbers and lab results only tell part of the story. What about how patients feel? How treatments impact their daily lives?...

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Charting the Landscape of Real-World Data in the United States

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